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COVER This image depicts a variety of sperm trying to reach an oocyte. Some sperm are abnormal, and some of those are patched up—alluding to treatments that can overcome some types of sperm abnormalities to achieve viable offspring. Conversely, some healthy sperm are blocked by walls, which represent contraception. See the special section on human reproduction beginning on page 148.
Illustration: Sara Gironi Carnevale
Science
- Volume 380|
- Issue 6641|
- 14 Apr 2023
COVER This image depicts a variety of sperm trying to reach an oocyte. Some sperm are abnormal, and some of those are patched up—alluding to treatments that can overcome some types of sperm abnormalities to achieve viable offspring. Conversely, some healthy sperm are blocked by walls, which represent contraception. See the special section on human reproduction beginning on page 148.
Illustration: Sara Gironi Carnevale
Special issue
Human reproduction
Introduction to Special Issue
The quest for safer and better planned reproduction
Reviews
Editorial
News
In Brief
In Depth
Expanded Ross Gyre would unleash warm water and disrupt ocean “conveyor belt”
Some 500 million years ago, early vertebrates acquired bacterial DNA that gave rise to a key vision gene
As systems dazzle, researchers worry about lack of safeguards and regulation
High-rises planned for “extraordinary” Native American site
Amyloid-clearing antibody lecanemab faces key FDA hearing in June
Feature
Radiocarbon timestamps left in ancient tree rings by cosmic ray bombardments can date historical events with unprecedented precision
Insights
Perspectives
Higher global temperatures are increasing the frequency of flash droughts
Skin microbiota can be engineered to induce antitumor T cells
Reduced expression of a platelet protein protects against thrombosis during chronic immobilization
A material with asymmetric mechanical responses offers diverse potential applications
Policy Forum
Aggregate metrics and lack of access to results limit understanding
Books et al.
A historian recounts the odorous origins of the first evidence for molecular structure
A polemical history shines a scientific spotlight on a remarkable and long-overlooked process
Letters
Research
Research Highlights
Highlights from the Science family of journals
Editors’ selections from the current scientific literature
Research Articles
The predicted rates, functional effects, and selection pressure of postzygotic mutations vary throughout the human life cycle.
Fossils of Morotopithecus suggest that the more upright stance of hominoids in the Miocene was shaped by dry and open forests.
A combination of data sources from fossil mammal sites pushes back the date of C4 grassland expansion in eastern Africa by over 10 million years.
Long-term immobility induces an antithrombotic platelet signature, helping to reduce thromboinflammation and thrombosis risk.
Anthropogenic climate change is driving a global transition toward more frequent flash droughts.
A uniform material with asymmetric mechanical response induces directional motion of various objects.
Combining direct imaging and astrometry techniques identifies a gas giant exoplanet orbiting a nearby star.
A system to express tumor antigens in the skin commensal bacterium Staphylococcus epidermidis elicits T cells that treat local and systemic tumors.
Careers
Working Life
Products & Materials
A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.
