Advertisement

COVER This image depicts a variety of sperm trying to reach an oocyte. Some sperm are abnormal, and some of those are patched up—alluding to treatments that can overcome some types of sperm abnormalities to achieve viable offspring. Conversely, some healthy sperm are blocked by walls, which represent contraception. See the special section on human reproduction beginning on page 148.

Illustration: Sara Gironi Carnevale

Science

  • Volume 380|
  • Issue 6641|
  • 14 Apr 2023

COVER This image depicts a variety of sperm trying to reach an oocyte. Some sperm are abnormal, and some of those are patched up—alluding to treatments that can overcome some types of sperm abnormalities to achieve viable offspring. Conversely, some healthy sperm are blocked by walls, which represent contraception. See the special section on human reproduction beginning on page 148.

Illustration: Sara Gironi Carnevale

Special issue

Human reproduction

Introduction to Special Issue

  • BY
    • Yevgeniya Nusinovich
  • : 148-149
  • Free
The quest for safer and better planned reproduction

Reviews

  • BY
    • Sarah J. Stock
    • Catherine E. Aiken
  • : 150-153
  • NO ACCESS
  • BY
    • Deborah J. Anderson
    • Daniel S. Johnston
  • : 154-158
  • NO ACCESS
  • BY
    • Qing Sang
    • Pierre F. Ray
    • Lei Wang
  • : 158-163
  • NO ACCESS
  • BY
    • Mary Herbert
    • Meenakshi Choudhary
    • Deidre Zander-Fox
  • : 164-167
  • NO ACCESS

Editorial

  • BY
    • H. Holden Thorp
  • : 115
  • FULL ACCESS

News

In Brief
  • : 116-117
In Depth
Expanded Ross Gyre would unleash warm water and disrupt ocean “conveyor belt”
Some 500 million years ago, early vertebrates acquired bacterial DNA that gave rise to a key vision gene
  • BY
    • Laurie Clarke
  • : 120-121
As systems dazzle, researchers worry about lack of safeguards and regulation
High-rises planned for “extraordinary” Native American site
Amyloid-clearing antibody lecanemab faces key FDA hearing in June
Feature
  • BY
    • Michael Price
  • : 124-128
Radiocarbon timestamps left in ancient tree rings by cosmic ray bombardments can date historical events with unprecedented precision
  • BY
    • Michael Price
  • : 127

Insights

Perspectives
  • BY
    • David W. Walker
    • Anne F. Van Loon
  • : 130-132
  • NO ACCESS
Higher global temperatures are increasing the frequency of flash droughts
  • BY
    • Sairaj M. Sajjath
    • Anita Gola
    • Elaine Fuchs
  • : 132-133
  • NO ACCESS
Skin microbiota can be engineered to induce antitumor T cells
  • BY
    • Mirta Schattner
  • : 133-134
  • NO ACCESS
Reduced expression of a platelet protein protects against thrombosis during chronic immobilization
  • BY
    • Bohan Sun
    • Sung Hoon Kang
  • : 135
  • NO ACCESS
A material with asymmetric mechanical responses offers diverse potential applications
Policy Forum
  • BY
    • Ryan Burnell
    • Wout Schellaert
    • John Burden
    • Tomer D. Ullman
    • Fernando Martinez-Plumed
    • Joshua B. Tenenbaum
    • Danaja Rutar
    • Lucy G. Cheke
    • Jascha Sohl-Dickstein
    • Melanie Mitchell
    • Douwe Kiela
    • Murray Shanahan
    • Ellen M. Voorhees
    • Anthony G. Cohn
    • Joel Z. Leibo
    • Jose Hernandez-Orallo
  • : 136-138
  • NO ACCESS
Aggregate metrics and lack of access to results limit understanding
Books et al.
  • BY
    • Michael D. Gordin
  • : 140
  • NO ACCESS
A historian recounts the odorous origins of the first evidence for molecular structure
  • : 140
  • NO ACCESS
  • BY
    • Lara Freidenfelds
  • : 141
  • NO ACCESS
A polemical history shines a scientific spotlight on a remarkable and long-overlooked process
Letters
  • BY
    • Wei Xu
    • Aifeng Tao
    • Jinhai Zheng
  • : 142
  • NO ACCESS
  • BY
    • Marcia C. Castro
    • Nísia Trindade
    • Arthur Chioro
    • José Gomes Temporão
    • Humberto Costa
    • Alexandre Padilha
    • Adriano Massuda
  • : 142-143
  • NO ACCESS
  • BY
    • Morten Dall
    • Maria Hauge Pedersen
  • : 143
  • Free

Research

Research Highlights
  • BY
    • Bianca Lopez
    • Sacha Vignieri
    • Mark Aldenderfer
    • Leslie K. Ferrarelli
    • Priscilla N. Kelly
    • Seth Thomas Scanlon
    • Keith T. Smith
    • H. Jesse Smith
    • Marc S. Lavine
    • Yevgeniya Nusinovich
    • Christiana N. Fogg
    • Fengnian Xia
  • : 168-170
  • Free
Highlights from the Science family of journals
  • BY
    • Yevgeniya Nusinovich
    • Stella M. Hurtley
    • Mattia Maroso
    • Bianca Lopez
    • Jelena Stajic
    • Keith T. Smith
    • Michael A. Funk
  • : 169-170
  • Free
Editors’ selections from the current scientific literature
Research Articles
  • BY
    • Nicole B. Rockweiler
    • Avinash Ramu
    • Liina Nagirnaja
    • Wing H. Wong
    • Michiel J. Noordam
    • Casey W. Drubin
    • Ni Huang
    • Brian Miller
    • Ellen Z. Todres
    • Katinka A. Vigh-Conrad
    • Antonino Zito
    • Kerrin S. Small
    • Kristin G. Ardlie
    • Barak A. Cohen
    • Donald F. Conrad
  • NO ACCESS
The predicted rates, functional effects, and selection pressure of postzygotic mutations vary throughout the human life cycle.
  • BY
    • Laura M. MacLatchy
    • Susanne M. Cote
    • Alan L. Deino
    • Robert M. Kityo
    • Amon A. T. Mugume
    • James B. Rossie
    • William J. Sanders
    • Miranda N. Cosman
    • Steven G. Driese
    • David L. Fox
    • April J. Freeman
    • Rutger J. W. Jansma
    • Kirsten E. H. Jenkins
    • Rahab N. Kinyanjui
    • William E. Lukens
    • Kieran P. McNulty
    • Alice Novello
    • Daniel J. Peppe
    • Caroline A. E. Strömberg
    • Kevin T. Uno
    • Alisa J. Winkler
    • John D. Kingston
  • NO ACCESS
Fossils of Morotopithecus suggest that the more upright stance of hominoids in the Miocene was shaped by dry and open forests.
  • BY
    • Daniel J. Peppe
    • Susanne M. Cote
    • Alan L. Deino
    • David L. Fox
    • John D. Kingston
    • Rahab N. Kinyanjui
    • William E. Lukens
    • Laura M. MacLatchy
    • Alice Novello
    • Caroline A. E. Strömberg
    • Steven G. Driese
    • Nicole D. Garrett
    • Kayla R. Hillis
    • Bonnie F. Jacobs
    • Kirsten E. H. Jenkins
    • Robert M. Kityo
    • Thomas Lehmann
    • Fredrick K. Manthi
    • Emma N. Mbua
    • Lauren A. Michel
    • Ellen R. Miller
    • Amon A. T. Mugume
    • Samuel N. Muteti
    • Isaiah O. Nengo
    • Kennedy O. Oginga
    • Samuel R. Phelps
    • Pratigya Polissar
    • James B. Rossie
    • Nancy J. Stevens
    • Kevin T. Uno
    • Kieran P. McNulty
  • : 173-177
  • NO ACCESS
A combination of data sources from fossil mammal sites pushes back the date of C4 grassland expansion in eastern Africa by over 10 million years.
  • BY
    • Manuela Thienel
    • Johannes B. Müller-Reif
    • Zhe Zhang
    • Vincent Ehreiser
    • Judith Huth
    • Khrystyna Shchurovska
    • Badr Kilani
    • Lisa Schweizer
    • Philipp E. Geyer
    • Maximilian Zwiebel
    • Julia Novotny
    • Enzo Lüsebrink
    • Gemma Little
    • Martin Orban
    • Leo Nicolai
    • Shaza El Nemr
    • Anna Titova
    • Michael Spannagl
    • Jonas Kindberg
    • Alina L. Evans
    • Orpheus Mach
    • Matthias Vogel
    • Steffen Tiedt
    • Steffen Ormanns
    • Barbara Kessler
    • Anne Dueck
    • Andrea Friebe
    • Peter Godsk Jørgensen
    • Monir Majzoub-Altweck
    • Andreas Blutke
    • Amin Polzin
    • Konstantin Stark
    • Stefan Kääb
    • Doris Maier
    • Jonathan M. Gibbins
    • Ulrich Limper
    • Ole Frobert
    • Matthias Mann
    • Steffen Massberg
    • Tobias Petzold
  • : 178-187
  • NO ACCESS
Long-term immobility induces an antithrombotic platelet signature, helping to reduce thromboinflammation and thrombosis risk.
  • BY
    • Xing Yuan
    • Yumiao Wang
    • Peng Ji
    • Peili Wu
    • Justin Sheffield
    • Jason A. Otkin
  • : 187-191
  • Free
Anthropogenic climate change is driving a global transition toward more frequent flash droughts.
  • BY
    • Xiang Wang
    • Zhihao Li
    • Shuxu Wang
    • Koki Sano
    • Zhifang Sun
    • Zhenhua Shao
    • Asuka Takeishi
    • Seishiro Matsubara
    • Dai Okumura
    • Nobuyuki Sakai
    • Takayoshi Sasaki
    • Takuzo Aida
    • Yasuhiro Ishida
  • : 192-198
  • NO ACCESS
A uniform material with asymmetric mechanical response induces directional motion of various objects.
  • BY
    • Thayne Currie
    • G. Mirek Brandt
    • Timothy D. Brandt
    • Brianna Lacy
    • Adam Burrows
    • Olivier Guyon
    • Motohide Tamura
    • Ranger Y. Liu
    • Sabina Sagynbayeva
    • Taylor Tobin
    • Jeffrey Chilcote
    • Tyler Groff
    • Christian Marois
    • William Thompson
    • Simon J. Murphy
    • Masayuki Kuzuhara
    • Kellen Lawson
    • Julien Lozi
    • Vincent Deo
    • Sebastien Vievard
    • Nour Skaf
    • Taichi Uyama
    • Nemanja Jovanovic
    • Frantz Martinache
    • N. Jeremy Kasdin
    • Tomoyuki Kudo
    • Michael McElwain
    • Markus Janson
    • John Wisniewski
    • Klaus Hodapp
    • Jun Nishikawa
    • Krzysztof Hełminiak
    • Jungmi Kwon
    • Masahiko Hayashi
  • : 198-203
  • NO ACCESS
Combining direct imaging and astrometry techniques identifies a gas giant exoplanet orbiting a nearby star.
  • BY
    • Y. Erin Chen
    • Djenet Bousbaine
    • Alessandra Veinbachs
    • Katayoon Atabakhsh
    • Alex Dimas
    • Victor K. Yu
    • Aishan Zhao
    • Nora J. Enright
    • Kazuki Nagashima
    • Yasmine Belkaid
    • Michael A. Fischbach
  • : 203-210
  • NO ACCESS
A system to express tumor antigens in the skin commensal bacterium Staphylococcus epidermidis elicits T cells that treat local and systemic tumors.

Careers

Working Life
  • BY
    • Jorge Cortez Campaña
  • : 214
  • Free

Products & Materials

  • : 211
  • Free
A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.

THIS WEEK’S PODCAST

Advertisement

Advertisement

Ad Placeholder ID

Advertisement